ContactLenseScience.com

July 5, 2009

Predictive Factors for Corneal Infiltrates With Continuous Wear of Silicone Hydrogel Contact Lenses

Dr. Loretta Szczotka-Flynn is an Associate Professor at the Department of Ophthalmology and visual Sciences at Case Western Reserve University and a leading US contact lens scientist and clinician. She reports on her breakthrough research on corneal infiltrates in low and high Dk contact lens materials. 

This Ciba Vision sponsored study explored risk for cornea infiltrative events in 30 day continuous wear patients.  The incidence of infiltrates increased over the three years of the study, peaking at 10% after 3 years.  Clinically significant infiltrates peaked at 3% after 2 and 3 years.


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June 5, 2009

Inflammatory Events in Lens Wear

Dr. Loretta Szczotka-Flynn is an Associate Professor at the Department of Ophthalmology and visual Sciences at Case Western Reserve University and a leading US contact lens scientist and clinician. She reports on her breakthrough research on corneal infiltrates in low and high Dk contact lens materials. 

Performing a meta-analysis of published data she determined that the risk of an infiltrative event is approximately 7 per 100 for low Dk extended wear and about 14 per 100 silicone hydrogel wearers per year.

Somewhat surprising was the doubled risk for infiltrative events in higher Dk silicone hydrogel wearers.  However these results are not mirrored by a reported increase in infection and may be due to the longer wearing period of silicone hydrogel lenses.


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Topics

     Basic Science
     Biocompatibility
     Disinfection
     Uptake/Release
     Wetting
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